人急性淋巴母細胞白血病細胞

HTB-176 H9 人急性淋巴母細胞白血病細胞

ATCC® Number: HTB-176™ Price: $268.00

Designations:

H9 [derivative of HuT 78]

Depositors: RC Gallo, M Popovic

Biosafety Level: 1

Shipped: frozen

Medium & Serum: See Propagation

Growth Properties: suspension

Organism: Homo sapiens （human）

Morphology: lymphoblast

HTB-176 H9 人急性淋巴母細胞白血病細胞

Source: Disease: lymphoma

Cell Type: cutaneous T lymphocyte;

Cellular Products: interleukin-2 （interleukin 2, IL-2）

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Applications: transfection host （Roche FuGENE® Transfection Reagents）

Receptors: interleukin 2 （IL-2）

Virus Susceptibility: human immunodeficiency virus 1 （HIV-1, also known as HTLV-III or LAV）

Tumorigenic: Yes

Antigen Expression: CD4;

HLA A1, B62, C3, DR4, DQ3

DNA Profile （STR）: Amelogenin: X,Y

CSF1PO: 11

D13S317: 8,12

D16S539: 11,12

D5S818: 11

D7S820: 8,11

THO1: 8,

9

TPOX: 8,9

vWA: 14,15

Cytogenetic Analysis: This is a near triploid cell line （modal number = 69; range = 58 to 74）. The frequency of higher ploidies is 2.5%. The line has an extremely complex karyotype with nearly 60% of the chromosomes in each cell being structurally altered marker chromosomes., Among the markers are t（3p4q）, t（5q6q）, t（5p6p）, i（18q）, i（18p）; t（4q7p）, and del（7）（q32）. The first four of these are usually paired. Normal N4, N5, N6, N7, N10, N13, N18, N19, N20 an X are absent.

Isoenzymes: AK-1, 0

HTB-176 H9